| DRUG 1
DC Bead® is a Drug Delivery Embolisation System capable of loading and releasing in a controlled manner high doses of chemotherapeutic agents.
DC Bead Indication for Use DC Bead is CE-Mark approved and is intended to be loaded with doxorubicin for the purpose of:
- Embolisation of vessels supplying malignant hypervascularised tumour(s)
- Delivery of a local, controlled, sustained dose of doxorubicin to the tumour(s)
- Doxorubicin maxium dose of 37.5mg/ml and 150mg per treatment with 4ml DC Bead
Interaction of Doxorubicin With DC Bead Sulphonate Groups
DC Bead Presentation
- Novel N-fil technology sulphonate modified hydrogel polymer
- Blue tinted to aid visualisation
- Delivered as vials containing 2ml Beads in 6ml saline
- Precise calibration to achieve an accurate level of embolisation
DRUG 2
DC Bead Indication for Use DC Bead is intended to be loaded with irinotecan for the purpose of:
- Embolisation of vessels supplying malignant ColoRectal cancer metastasised to the liver (mCRC)
- Delivery of a local, controlled, sustained dose of irinotecan to hepatic metastases of colorectal cancer
DC Bead Presentation
- Novel N-fil technology sulphonate modified hydrogel polymer
- Blue tinted to aid visualisation
- Delivered as vials containing 2ml Beads in 6ml saline
- Precise calibration for an accurate embolisation
Improved response, no compromise in safety “I know I would not be here today feeling so well if I had not undergone the treatment… apart from a bit of pain I recovered remarkably quickly… it has changed my life. I am 86 this year and feel very well.”
Mrs DS ( Devon, UK), was first treated with DC Bead 4 years ago in 2005 for multifocal HCC.
DC Bead with its superior pharmacokinetic profile can show a signifi cant improvement in response (p<0.05) in more advanced and fragile patients without a compromise in safety. Until now these patients have not been considered as candidates for chemoembolisation (ref AASLD guideline).
More advanced patients receiving DC Bead were given a mean dose of 120mg, 33% more than the control arm yet demonstrated no deterioration in safety and a signifi cant advantage in response. | 
